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Franklin's Photo 51 shows the mysterious "X" shape that inspired Watson and Crick to visualize the double helix structure of DNA. She was able to get this remarkable image—the clearest image of DNA ever created up until that time—with her advanced techniques of X-ray diffraction. Using Franklin's image as physical evidence, Watson and Crick then went on to publish their Nobel Prize-winning theoretical structure of DNA in Nature in 1953.
For a detailed look at this image, see Anatomy of Photo 51.
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